Duovir – Lamivudine + Zidovudine (Generic Combivir)

Duovir – Lamivudine + Zidovudine (Generic Combivir)

Brand Name: Duovir
Generic Name:
Lamivudine 150 mg  + Zidovudine 300 mg USP
Contents:
Lamivudine 150 mg  + Zidovudine 300 mg USP
Form: Tablets
Manufacturer Cipla
Other Brand Name: Generic Combivir
Pricing: Price Per Pack of 60 Tablets

DUOVIR Tablets are indicated for the treatment of HIV infection, as part of combination therapy.

DOSAGE AND ADMINISTRATION

Adults and Adolescents
The recommended oral dose of DUOVIR Tablets for adults and adolescents (at least 12 years of age) is one tablet (containing 150 mg of lamivudine and 300 mg of zidovudine) twice daily.

Dose Adjustment: Because DUOVIR Tablets are a fixed-dose combination, they should not be prescribed for patients requiring dosage adjustment such as those with reduced renal function (creatinine clearance <50 mL/min) or those experiencing dose-limiting adverse events.

A reduction in the daily dose of zidovudine may be necessary in patients with mild to moderate impaired hepatic function or liver cirrhosis. Because DUOVIR Tablets are a fixed-dose combination that cannot be adjusted for this patient population, they are not recommended for patients with impaired hepatic function.

CONTRAINDICATIONS

DUOVIR Tablets are contraindicated in patients with previously demonstrated clinically significant hypersensitivity (eg, anaphylaxis, Stevens-Johnson Syndrome) to any of the components of the product.