Indivan (Crixivan Generic) – Indinavir

Indivan (Crixivan Generic) – Indinavir

Brand Name: Indivan
Strength: 400mg
Contents: Indinavir 400mg
Form: Tablets
Manufacturer Cipla
Other Brand Name: Crixivan
Pricing: Pack of 30 Tabs

 INDIVAN in combination with antiretroviral agents is indicated for the treatment of HIV infection.

DOSAGE AND ADMINISTRATION
The recommended dosage of indinavir is 800 mg (two 400 mg capsules) orally every 8 hours. For optimal absorption, indinavir should be administered without food but with water 1 hour before or 2 hours after a meal. To ensure adequate hydration, it is recommended that the patient drink at least 1.5 litres (approximately 48 ounces) of liquids during the course of 24 hours.

CONTRAINDICATIONS
INDIVAN is contraindicated in patients with clinically significant hypersensitivity to any of its components.

Inhibition of CYP3A4 by indinavir can result in elevated plasma concentrations of the following drugs, potentially causing serious or life-threatening reactions:

OVERDOSAGE
There have been more than 60 reports of acute or chronic human overdosage (up to 23 times the recommended total daily dose of 2400 mg) with indinavir. The most commonly reported symptoms were renal (e.g., nephrolithiasis,/urolithiasis, flank pain, haematuria) and gastrointestinal (e.g., nausea, vomiting, diarrhoea).

It is not known whether indinavir is dialysable by peritoneal or haemodialysis.