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Rhoclone – Anti Rho-D Immunoglobulin Injection
Rhoclone – Anti Rho-D Immunoglobulin Injection
| Rhoclone : | Anti Rho-D Immunoglobulin Injection (Monoclonal) |
| Brand Name : | RHOCLONE |
| Strength Available : | 150 mcg / 300 mcg |
| Manufactured By: | Bharat Serums And Vaccines LTD |
| Other Brand Names : | BayRHo-D, Gamulin Rh, HypRho-D Mini-Dose, Mini-Gamulin Rh, WinRho SDF (Cangene), Partobulin SDF (Baxter) and Rhesonativ (Octapharma) |
About Rhoclone Injection
Rhoclone is a sterile lyophilised powder of Monoclonal Human Anti-rhesus Immunoglobulin (lgG1) containing antibodies to Rho-D. It is derived from stable heterohybridoma (human – mouse) cell line HG-92 and purified using protein affinity chromatography.
Rho(D) Immune Globulin is a medicine given by intramuscular injection that is used to prevent the immunological condition known as Rhesus disease (or hemolytic disease of newborn). The medicine is a solution of IgG anti-D (anti-RhD) antibodies that bind to, and lead to the destruction of, fetal Rh D positive red blood cells that have passed from the fetal circulation to the maternal circulation. Therefore, in a Rhesus negative mother it can prevent sensitization of the maternal immune system to Rh D antigens, which can cause rhesus disease in the current or in subsequent pregnancies. With the widespread use of Rho(D) Immune Globulin, Rh disease of the fetus and newborn has almost disappeared.
