Rhoclone – Anti Rho-D Immunoglobulin Injection

Rhoclone – Anti Rho-D Immunoglobulin Injection

Rhoclone : Anti Rho-D Immunoglobulin Injection (Monoclonal)
Brand Name : RHOCLONE
Strength Available : 150 mcg / 300 mcg
Manufactured By: Bharat Serums And Vaccines LTD
Other Brand Names : BayRHo-D, Gamulin Rh, HypRho-D Mini-Dose, Mini-Gamulin Rh, WinRho SDF (Cangene), Partobulin SDF (Baxter) and Rhesonativ (Octapharma)

About Rhoclone Injection
Rhoclone is a sterile lyophilised powder of Monoclonal Human Anti-rhesus Immunoglobulin (lgG1) containing antibodies to Rho-D. It is derived from stable heterohybridoma (human – mouse) cell line HG-92 and purified using protein affinity chromatography.

Rho(D) Immune Globulin is a medicine given by intramuscular injection that is used to prevent the immunological condition known as Rhesus disease (or hemolytic disease of newborn). The medicine is a solution of IgG anti-D (anti-RhD) antibodies that bind to, and lead to the destruction of, fetal Rh D positive red blood cells that have passed from the fetal circulation to the maternal circulation. Therefore, in a Rhesus negative mother it can prevent sensitization of the maternal immune system to Rh D antigens, which can cause rhesus disease in the current or in subsequent pregnancies. With the widespread use of Rho(D) Immune Globulin, Rh disease of the fetus and newborn has almost disappeared.